Payment Type: | L/C,T/T,D/P,Paypal,Money Gram,Western Union |
---|---|
Incoterm: | FOB,CFR,CIF,EXW,FCA,CPT,CIP |
Min. Order: | 10 Gram |
Delivery Time: | 7 Days |
Basic Info
Model No.: TF-2039
Type: Synthesis Material Intermediates
Appearance: Powder
Quality: Technical
Colour: White
Additional Info
Packaging: As Buyer's Request
Productivity: 100Ton
Brand: Tianfu
Transportation: Ocean,Land,Air,DHL,TNT
Place of Origin: China
Supply Ability: 50Ton
Certificate: ISO
Port: Shanghai port,Qingdao port
Product Description
Description
Dyclonine Hydrochloride 536-43-6
Dyclonine Hydrochloride
536-43-6
MW: 325.9
MSDS: Avaiable
MF: C18H27NO2 HCl
Sample: Avaiable
Category: API
Min order: 10grams
Quality standard: USP Place of Origin:China
Appearance Dyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter
throat
lozenge.[1] It is also found in some varieties of the Cepacol sore
throat spray. It is a local anesthetic, used topically as the
hydrochloride salt
Applications Pharmaceutical raw materials Used as a local anesthetic.
Dyclonine Hydrochloride 536-43-6
Function
Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.
Specification
Item |
Specifications |
Results |
Appearance |
A white crystalline powder |
White crystalline powder |
Identification |
IR; HPLC |
Conforms |
Sulphates |
NMT0.05% |
Conforms |
Toluene |
NMT890ppm |
Not detected |
Methanol |
NMT3000ppm |
Not detected |
Related substances (TLC) |
NMT1.0% |
Conforms |
Loss on drying |
NMT0.5% |
0.07% |
Sulphated ash |
NMT0.1% |
0.09% |
Ammonium |
NMT0.08% |
Conforms |
Heavy metals |
NMT0.001% |
Conforms |
Microbiology |
Total bacterial count:<1000CFU/g |
30CFU/g |
Total Fungus count: <100CFU/g |
<10 CFU/g |
|
Escherichia coli:Not detected |
Not detected |